Circulation Researchand Human Genetic Studies
نویسندگان
چکیده
منابع مشابه
Circulation Research and human genetic studies.
June 26, 2010, marked the 10th anniversary of the completion of the draft sequence of the human genome,1,2 an achievement that was the pinnacle of the Human Genome Project, started approximately 11 years earlier and officially completed in 2003.1–3 The Human Genome Project offered the first systematic glimpses into the sequence of a haploid genome.1–3 It facilitated immensely the identification...
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We reviewed the literature on human cerebral circulation and oxygen metabolism, as measured by positron emission tomography (PET), with respect to normal values and of regulation of cerebral circulation. A multicenter study in Japan showed that between-center variations in cerebral blood flow (CBF), cerebral blood volume (CBV), cerebral oxygen extraction fraction (OEF) and cerebral metabolic ra...
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the Journal of Craniofacial Genetics and Developmental Biology, 1985, vol 5, is dedicated to the memory of Dr Samuel Pruzansky, an internationally renowned worker in the field of craniofacial malformations until his death in 1984. Among his many achievements, Dr Pruzansky organised the first international symposium on craniofacial malformations in 1959 and founded the first Center for Craniofac...
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Human prion diseases are fatal neurodegenerative disorders that are characterized by spongiform changes, astrogliosis, and the accumulation of an abnormal prion protein (PrP(Sc)). Approximately 10%-15% of human prion diseases are familial variants that are caused by pathogenic mutations in the prion protein gene (PRNP). Point mutations or the insertions of one or more copies of a 24 bp repeat a...
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Genetic aberrations in sarcomas 10 2.1. Cytogenetic alterations 10 2.2. Molecular genetic changes 13 2.2.1. Structural alterations of cellular proto-oncogenes 13 2.2.2. Gene amplifications 13 2.2.3. Alterations of tumor suppressor genes and loss of 17 DNA sequences 2.3. Hereditary predisposition 18 3. DNA amplification 19 3.1. Structure and mechanisms of DNA amplification 20 4. Methods for dete...
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ژورنال
عنوان ژورنال: Circulation Research
سال: 2010
ISSN: 0009-7330,1524-4571
DOI: 10.1161/circresaha.110.226258